The current review, for that reason, demonstrates that, in the rat hippocampus, two nAChR subtypes are existing on GABAergic nerve endings where they induce enhancement of endogenous GABA release by means of two distinctive mechanisms

As for the molecular mechanisms, the 5IA85380-evoked, carrier-impartial endogenous GABA release was exterior Ca2+-dependent and fully blocked by Cd2+, although dantrolene, thapsigargin and xestospongin C have been devoid of any…