Product Name :
MMP-7 (catalytic domain) (human), (recombinant)
Sequence:
Purity:
≥95% (SDS-PAGE)
Molecular Weight:
20.4 kDa
Solubility :
Appearance:
Use/Stability :
Description:
CAS :
Solubility:
Formula:
Additional Information :
| Activity Preincubation of MMP-7 catalytic domain at 19nM with the broad-spectrum inhibitor GM6001 at 100nM for 1 hour completely inhibits enzymatic activity.{{1476074-39-1} medchemexpress|{1476074-39-1} Purity & Documentation|{1476074-39-1} Purity|{1476074-39-1} manufacturer} | Alternative Name Matrix metalloproteinase 7, Matrilysin, Pump | Application Notes Useful tool to study enzyme kinetics, cleave target substrates, and screen for inhibitors.{{83883-10-7} web|{83883-10-7} Biological Activity|{83883-10-7} Description|{83883-10-7} custom synthesis} | Formulation Liquid.PMID:31474151 In 50 mM Tris-HCl pH 7.5, 5 mM CaCl2, 300 mM NaCl, 20 µM ZnCl2, 0.5% Brij-35, and 30% glycerol. | MW 20.4 kDa | Purity ≥95% (SDS-PAGE) | Purity Detail Purified by multi-step chromatography. | Source Produced in E. coli. Active Matrix Metalloproteinase-7 (MMP-7, matrilysin, pump) catalytic domain from human cDNA. The enzyme consists of the catalytic domain of human MMP-7 (Tyr95-Lys267, NM_002423) with a C-terminal purification tag. | Specific Activity ≥200 pmol/min/µg at 37°C using the colorimetric thiopeptolide Ac-Pro-Leu-Gly-S-Leu-Leu-GlyOEt (100 µM; Prod. No. BML-P125) as substrate. | UniProt ID P09237