Product Name :
Matrix Metalloproteinase-1 (MMP-1) fluorometric drug discovery kit
Sequence:
Purity:
Molecular Weight:
Solubility :
Appearance:
Use/Stability :
Description:
A QUANTIZYME® Assay System.{{114977-28-5} site|{114977-28-5} Biological Activity|{114977-28-5} In Vitro|{114977-28-5} supplier} The MMP-1 Fluorometric (also known as fluorimetric) Drug Discovery Kit is a complete assay system designed to screen inhibitors of matrix metalloproteinase-1 (MMP-1, interstitial collagenase) using a quenched fluorogenic peptide: OMNIMMP® fluorogenic substrate Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH.{{1264737-26-9} medchemexpress|{1264737-26-9} Purity & Documentation|{1264737-26-9} In Vivo|{1264737-26-9} supplier} Mca fluorescence is quenched by the Dpa group until cleavage by MMPs at the Gly-Leu bond separates the two moieties.PMID:31082173 The assays are performed in a convenient 96-well microplate format. The kit is useful to screen inhibitors of MMP-1, a potential therapeutic target. Included are active enzyme, assay buffer, a prototypic control inhibitor (NNGH3), and a detailed instruction booklet.
CAS :
Solubility:
Formula:
Additional Information :
| Alternative Name Interstitial collagenase, Fibroblast collagenase | Application Fluorescent detection, HTS | Contents MMP-1 enzyme, substrate, calibration standard, inhibitor, assay buffer, 96-well white microplate. | UniProt ID P03956