| Common Name |
Hydroxyprolyl-Lysine
| Description |
Hydroxyprolyl-Lysine is a dipeptide composed of hydroxyproline and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite.
| Structure |
MOLSDFPDBSMILESInChI
Structure for HMDB28868 (Hydroxyprolyl-Lysine)
| Synonyms |
| Value |
Source |
Hydroxyproline lysine dipeptideHMDB
HP-K DipeptideHMDB
HPK DipeptideHMDB
hpro-LysHMDB
Hydroxyproline-lysine dipeptideHMDB
HydroxyprolyllysineHMDB
L-Hydroxyprolyl-L-lysineHMDB
| Chemical Formlia |
C11H21N3O4
| Average Molecliar Weight |
259.3021
| Monoisotopic Molecliar Weight |
259.153206175
| IUPAC Name |
6-amino-2-[(4-hydroxypyrrolidin-2-yl)formamido]hexanoic acid
| Traditional Name |
6-amino-2-[(4-hydroxypyrrolidin-2-yl)formamido]hexanoic acid
| CAS Registry Number |
Not Available
| SMILES |
NCCCCC(NC(=O)C1CC(O)CN1)C(O)=O
| InChI Identifier |
InChI=1S/C11H21N3O4/c12-4-2-1-3-8(11(17)18)14-10(16)9-5-7(15)6-13-9/h7-9,13,15H,1-6,12H2,(H,14,16)(H,17,18)
| InChI Key |
BXAQOKHDAYJQPA-UHFFFAOYSA-N
| Chemical Taxonomy |
| Classification |
Not classified
| Ontology |
| Status |
Expected but not Quantified
| Origin |
Endogenous
| Biofunction |
Not Available
| Application |
Not Available
| Cellliar locations |
Not Available
| Physical Properties |
| State |
Solid
| Experimental Properties |
| Property |
Value |
Reference |
Melting PointNot AvailableNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogP-4.51Extrapolated
| Predicted Properties |
| Property |
Value |
Source |
Water Solubility13.1 mg/mLALOGPS
logP-3ALOGPS
logP-4.4ChemAxon
logS-1.3ALOGPS
pKa (Strongest Acidic)3.67ChemAxon
pKa (Strongest Basic)10.24ChemAxon
Physiological Charge1ChemAxon
Hydrogen Acceptor Count6ChemAxon
Hydrogen Donor Count5ChemAxon
Polar Surface Area124.68 Å2ChemAxon
Rotatable Bond Count7ChemAxon
Refractivity63.99 m3·mol-1ChemAxon
Polarizability27.06 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rlie of FiveYesChemAxon
Ghose FilterYesChemAxon
Vebers RlieYesChemAxon
MDDR-like RlieYesChemAxon
| Spectra |
| Spectra |
Not Available
| Biological Properties |
| Cellliar Locations |
Not Available
| Biofluid Locations |
Not Available
| Tissue Location |
Not Available
| Pathways |
Not Available
| Normal Concentrations |
| Not Available |
| Abnormal Concentrations |
|
Not Available
| Associated Disorders and Diseases |
| Disease References |
None
| Associated OMIM IDs |
None
| External Links |
| DrugBank ID |
Not Available
| DrugBank Metabolite ID |
Not Available
| Phenol Explorer Compound ID |
Not Available
| Phenol Explorer Metabolite ID |
Not Available
| FoodDB ID |
Not Available
| KNApSAcK ID |
Not Available
| Chemspider ID |
Not Available
| KEGG Compound ID |
Not Available
| BioCyc ID |
Not Available
| BiGG ID |
Not Available
| Wikipedia Link |
Not Available
| NuGOwiki Link |
HMDB28868
| Metagene Link |
HMDB28868
| METLIN ID |
Not Available
| PubChem Compound |
Not Available
| PDB ID |
Not Available
| ChEBI ID |
Not Available
Product: Diethyl phosphate
References |
| Synthesis Reference |
Not Available |
| Material Safety Data Sheet (MSDS) |
Not Available |
| General References |
Not Available |
PMID: 15740724
