Product Name :
Z-VAD-FMK (Ready-to-Use)
Sequence:
Z-Val-Ala-Asp-fluoromethylketone
Purity:
≥99% (TLC)
Molecular Weight:
467.5
Solubility :
Appearance:
Use/Stability :
As indicated on product label or CoA when stored as recommended.
Description:
Caspase inhibitor Synthetic peptide that irreversibly inhibits ICE-family protease/caspase activity and blocks apoptosis. The inhibitor is designed as a methyl ester to facilitate cell permeability.755038-65-4 site Figure: Apoptosis was induced in Jurkat cells with camptothecin (2µM) for 6 hours in the presence of various concentrations of Z-VAD-FMK .129298-91-5 MedChemExpress Caspase activity was measured using Caspase-3 Fluorometric Assay Kit according to the kit instructions.””””” Figure: Apoptosis was induced in Jurkat cells with camptothecin (2µM) for 6 hours in the presence of various concentrations of Z-VAD-FMK . Caspase activity was measured using Caspase-3 Fluorometric Assay Kit according to the kit instructions.PMID:30844197 ”””””
CAS :
Solubility:
Formula:
C22H30FN3O7
Additional Information :
| Alternative Name Caspase family inhibitor (fluoromethylketone) | Formula C22H30FN3O7 | Formulation Liquid. In DMSO. | MW 467.5 | Purity ≥99% (TLC) | Sequence Z-Val-Ala-Asp-fluoromethylketone | Source Synthetic | Technical Info / Product Notes We recommend a final concentration of 2-10µM for inhibiting caspase activity in Jurkat cell culture. The optimal doses may vary for different cells and culture conditions.