Product Name :
SMS2-IN-2
Description:
SMS2-IN-2 is a potent, highly selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM and 56 μM for SMS2 and SMS1, respectively. Anti-chronic inflammatory activity.
CAS:
2241838-28-6
Molecular Weight:
369.78
Formula:
C19H13ClFN3O2
Chemical Name:
4-[(2-chloro-5-fluorophenyl)methoxy]-N-(pyridin-3-yl)-1,2-benzoxazol-3-amine
Smiles :
FC1=CC(COC2C=CC=C3ON=C(NC4=CN=CC=C4)C=23)=C(Cl)C=C1
InChiKey:
VZWFUUUUCXTDJT-UHFFFAOYSA-N
InChi :
InChI=1S/C19H13ClFN3O2/c20-15-7-6-13(21)9-12(15)11-25-16-4-1-5-17-18(16)19(24-26-17)23-14-3-2-8-22-10-14/h1-10H,11H2,(H,23,24)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{IL-2 Protein, Human} web|{IL-2 Protein, Human} Protocol|{IL-2 Protein, Human} In stock|{IL-2 Protein, Human} custom synthesis|{IL-2 Protein, Human} Epigenetics}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
SMS2-IN-2 is a potent, highly selective and orally active sphingomyelin synthase 2 (SMS2) inhibitor, with IC50s of 100 nM and 56 μM for SMS2 and SMS1, respectively.{{Tenofovir} MedChemExpress|{Tenofovir} HBV|{Tenofovir} Protocol|{Tenofovir} Description|{Tenofovir} custom synthesis|{Tenofovir} Cancer} Anti-chronic inflammatory activity.PMID:32964802 |Product information|CAS Number: 2241838-28-6|Molecular Weight: 369.78|Formula: C19H13ClFN3O2|Chemical Name: 4-[(2-chloro-5-fluorophenyl)methoxy]-N-(pyridin-3-yl)-1,2-benzoxazol-3-amine|Smiles: FC1=CC(COC2C=CC=C3ON=C(NC4=CN=CC=C4)C=23)=C(Cl)C=C1|InChiKey: VZWFUUUUCXTDJT-UHFFFAOYSA-N|InChi: InChI=1S/C19H13ClFN3O2/c20-15-7-6-13(21)9-12(15)11-25-16-4-1-5-17-18(16)19(24-26-17)23-14-3-2-8-22-10-14/h1-10H,11H2,(H,23,24)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 125 mg/mL (338.04 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|SMS2-IN-2 (Compound 15w; 20, 50 mg/kg/day, p.o. for 6 weeks) reduces chronic inflammation in the db/db mice.|Products are for research use only. Not for human use.|