Product Name :
Anti-SLAMF7, Human antibody
Applications:
ELISA,Flow Cyt
Reactivity :
Human
Conjugate:
Unconjugated
Advantages :
High lot-to-lot consistencyIncreased sensitivity and higher affinityAnimal-free production
Description:
| Description: Anti-SLAMF7, Human antibody is designed for detecting human SLAMF7 specifically. Based on ELISA and/or FCM, Anti-SLAMF7, Human antibody reacts with human SLAMF7 specifically. | Immunogen: Recombinant human SLAMF7 | Host: Alpaca pacous | Isotype: Human IgG1 | Conjugate: Unconjugated | Specificity: Human SLAMF7 | Purity: Recombinant Expression and Affinity purified | Concentration: 1mg/ml | Formation: Liquid, 10mM PBS (pH 7.5), 0.05% sucrose, 0.1% trehalose, 0.01% proclin300, 50% Glycerol | Storage: Store at –20 °C, (Avoid freeze / thaw cycles) | Background:SLAMF7 contains one Ig-like C2-type (immunoglobulin-like) domain. Isoform 1 mediates NK cell activation through a SAP-independent extracellular signal-regulated ERK-mediated pathway. It may play a role in lymphocyte adhesion. Isoform 3 does not mediate any activation. SAP can bind the cytoplasmic tail of isoform 1 when phosphorylated in the presence of Fyn (in vitro). SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Expression was detected in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-, or T-cell lines. The isoform 3 is expressed at much lower level than isoform 1. There are three named isoforms.
Description2 :
Anti-SLAMF7, Human antibody is designed for detecting human SLAMF7 specifically. Based on ELISA and/or FCM, Anti-SLAMF7, Human antibody reacts with human SLAMF7 specifically.
Immunogen:
Recombinant human SLAMF7
Host :
Alpaca pacous
Isotype:
Human IgG1
Purity :
Recombinant Expression and Affinity purified
Buffer :
Storage :
Store at –20 °C, (Avoid freeze / thaw cycles)
Function:
ELISA: 1:4,000-1:10000Flow Cytometry：1:200-1:1000Dilution factors are presented in the form of a range because the optimal dilution is a function of many factors, such as antigen density, permeability, etc.{{1809427-19-7} web|{1809427-19-7} Purity & Documentation|{1809427-19-7} References|{1809427-19-7} supplier} The actual dilution used must be determined empirically.{{698394-73-9} site|{698394-73-9} Protocol|{698394-73-9} Purity|{698394-73-9} supplier}