Product Name :
TUG-424
CAS No.:
1082058-99-8
Purity :
≥98.0%
Shipping:
Room temperature in the continental U.S. Other areas may vary.
Storage :
Powder: -20°C, 3 yearsIn solvent: -80°C, 6 months; -20°C, 1 month
SMILES:
OC(CCC(C=C1)=CC=C1C#CC2=C(C)C=CC=C2)=O
Product Description :
TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM. TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity. TUG-424 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Formula:
C18H16O2
Molecular Weight :
264.{{217094-32-1} MedChemExpress|{217094-32-1} Technical Information|{217094-32-1} Purity|{217094-32-1} manufacturer} 32
Synonyms:
Additional Information:
|CAS No.{{1841409-92-4} MedChemExpress|{1841409-92-4} Biological Activity|{1841409-92-4} In Vitro|{1841409-92-4} manufacturer} 1082058-99-8 ; |Formula C18H16O2 ; |Molecular Weight 264.32 ; |SMILES OC(CCC(C=C1)=CC=C1C#CC2=C(C)C=CC=C2)=O ; |Target Free Fatty Acid Receptor ; |Product Description TUG-424 is a potent and selective free fatty acid receptor 1 (FFA1/GPR40) agonist with an EC50 of 32 nM.PMID:31194403 TUG-424 significantly increases glucose-stimulated insulin secretion at 100 nM. TUG-424 may serve to explore the role of FFA1 in metabolic diseases such as diabetes or obesity. TUG-424 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. ; |Format Solid ; |Color White to off-white ; |Purity ≥98.0% ; |Shipping Room temperature in the continental U.S. Other areas may vary. ; |Storage Powder: -20°C, 3 yearsIn solvent: -80°C, 6 months; -20°C, 1 month