Product Name :
GSK-J2
Description:
GSK-J2 is an isomer of GSK-J1 that does not have any specific activity. GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.
CAS:
1394854-52-4
Molecular Weight:
389.45
Formula:
C22H23N5O2
Chemical Name:
3-{[2-(pyridin-3-yl)-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoic acid
Smiles :
OC(=O)CCNC1=CC(=NC(=N1)C1=CN=CC=C1)N1CCC2=CC=CC=C2CC1
InChiKey:
LJIFOCRGDDQFJF-UHFFFAOYSA-N
InChi :
InChI=1S/C22H23N5O2/c28-21(29)7-11-24-19-14-20(26-22(25-19)18-6-3-10-23-15-18)27-12-8-16-4-1-2-5-17(16)9-13-27/h1-6,10,14-15H,7-9,11-13H2,(H,28,29)(H,24,25,26)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Coelenterazine} medchemexpress|{Coelenterazine} Metabolic Enzyme/Protease|{Coelenterazine} Purity & Documentation|{Coelenterazine} In Vitro|{Coelenterazine} manufacturer|{Coelenterazine} Epigenetic Reader Domain}
Shelf Life:
≥360 days if stored properly.{{CASP8-IN-1} site|{CASP8-IN-1} Apoptosis|{CASP8-IN-1} TGF-beta/Smad|{CASP8-IN-1} Technical Information|{CASP8-IN-1} In Vitro|{CASP8-IN-1} custom synthesis}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
GSK-J2 is an isomer of GSK-J1 that does not have any specific activity.PMID:31085260 GSK-J1 is a potent inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A.|Product information|CAS Number: 1394854-52-4|Molecular Weight: 389.45|Formula: C22H23N5O2|Chemical Name: 3-{[2-(pyridin-3-yl)-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoic acid|Smiles: OC(=O)CCNC1=CC(=NC(=N1)C1=CN=CC=C1)N1CCC2=CC=CC=C2CC1|InChiKey: LJIFOCRGDDQFJF-UHFFFAOYSA-N|InChi: InChI=1S/C22H23N5O2/c28-21(29)7-11-24-19-14-20(26-22(25-19)18-6-3-10-23-15-18)27-12-8-16-4-1-2-5-17(16)9-13-27/h1-6,10,14-15H,7-9,11-13H2,(H,28,29)(H,24,25,26)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|