Year: 2024

Product Name : SauristolactamDescription:Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells. Sauristolactam also inhibits…

Product Name : FPH2 (BRD-9424)Description:FPH2 (BRD-9424) is a small molecule, which promotes differentiation of iPS-derived hepatocytes.CAS: 957485-64-2Molecular Weight:353.83Formula: C14H16ClN5O2SChemical Name: 4-{[(5-chloro-2-methoxyphenyl)carbamothioyl]amino}-1-ethyl-1H-pyrazole-3-carboxamideSmiles : CCN1C=C(NC(=S)NC2C=C(Cl)C=CC=2OC)C(=N1)C(N)=OInChiKey: PCHRYHSDDPPZBV-UHFFFAOYSA-NInChi : InChI=1S/C14H16ClN5O2S/c1-3-20-7-10(12(19-20)13(16)21)18-14(23)17-9-6-8(15)4-5-11(9)22-2/h4-7H,3H2,1-2H3,(H2,16,21)(H2,17,18,23)Purity: ≥98% (or refer to…

Product Name : PD-1/PD-L1-IN-8Description:PD-1/PD-L1-IN-8 (example 24) is a PD-1/PD-L1 inhibitor, with an IC50

Product Name : 3, 3'-DifluorobenzaldazineDescription:3,3'-Difluorobenzaldazine (DFB) is a selective positive allosteric modulator of mGluR5. 3,3'-Difluorobenzaldazine potentiates 3- to 6-fold action for mGlu5 agonists (Glutamate, Quisqualate, and 3,5-Dihydroxyphenylglycine), with EC50s in…

Product Name : GNE-207Description:GNE-207 is a potent, selective and orally bioavailable inhibitor of the bromodomain of CBP, with an IC50 of 1 nM, exhibits a selectively index of >2500-fold against BRD4…

Product Name : Tazemetostat trihydrochlorideDescription:Tazemetostat trihydrochloride (EPZ-6438 trihydrochloride) is a potent, selective and orally available EZH2 inhibitor. Tazemetostat trihydrochloride inhibits the activity of human polycomb repressive complex 2 (PRC2)-containing wild-type…

Product Name : FAK ligand-Linker Conjugate 1Description:FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP).…

Product Name : Chlorimuron-ethylDescription:Chlorimuron-ethyl induces oxidative stress. Chlorimuron-ethyl is an important herbicide that has been widely used in soybean production.CAS: 90982-32-4Molecular Weight:414.82Formula: C15H15ClN4O6SChemical Name: ethyl 2-({[(4-chloro-6-methoxypyrimidin-2-yl)carbamoyl]amino}sulfonyl)benzoateSmiles : COC1=CC(Cl)=NC(NC(=O)NS(=O)(=O)C2=CC=CC=C2C(=O)OCC)=N1InChiKey: NSWAMPCUPHPTTC-UHFFFAOYSA-NInChi :…

Product Name : Glyoxalase I inhibitorDescription:Glyoxalase I inhibitor (free base) is a potent Glyoxalase I (GLO1) inhibitor, candidate for anticancer agents.CAS: 221174-33-0Molecular Weight:613.91Formula: C21H30BrClN4O8SChemical Name: ethyl (2S)-2-amino-4-{[(1R)-2-{[(4-bromophenyl)(hydroxy)carbamoyl]sulfanyl}-1-[(2-ethoxy-2-oxoethyl)carbamoyl]ethyl]carbamoyl}butanoate hydrochlorideSmiles : Cl.CCOC(=O)CNC(=O)[C@H](CSC(=O)N(O)C1C=CC(Br)=CC=1)NC(=O)CC[C@H](N)C(=O)OCCInChiKey:…

Product Name : WIN54954Description:WIN54954 is a broad-spectrum antipicornavirus drug. WIN 54 954 is a potent antiviral agent with a highly significant effect on survival in CBV-induced myocarditis in the A/J…