Product Name :
N-Desmethyl Pimavanserin
Description:
N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.
CAS:
639863-77-7
Molecular Weight:
413.53
Formula:
C24H32FN3O2
Chemical Name:
1-[(4-fluorophenyl)methyl]-3-{[4-(2-methylpropoxy)phenyl]methyl}-1-(piperidin-4-yl)urea
Smiles :
CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCNCC2)C=C1
InChiKey:
CJAUQHPXNICIJI-UHFFFAOYSA-N
InChi :
InChI=1S/C24H32FN3O2/c1-18(2)17-30-23-9-5-19(6-10-23)15-27-24(29)28(22-11-13-26-14-12-22)16-20-3-7-21(25)8-4-20/h3-10,18,22,26H,11-17H2,1-2H3,(H,27,29)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.{{Famotidine} web|{Famotidine} GPCR/G Protein|{Famotidine} Technical Information|{Famotidine} Purity|{Famotidine} custom synthesis|{Famotidine} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.{{Moxetumomab} web|{Moxetumomab} Immunology/Inflammation|{Moxetumomab} Technical Information|{Moxetumomab} In stock|{Moxetumomab} manufacturer|{Moxetumomab} Autophagy}
Additional information:
N-Desmethyl Pimavanserin is the active metabolite of Pimavanserin. Pimavanserin is a selective inverse agonist of the 5-HT2A receptor with pIC50 and pKd of 8.73 and 9.3, respectively.|Product information|CAS Number: 639863-77-7|Molecular Weight: 413.53|Formula: C24H32FN3O2|Chemical Name: 1-[(4-fluorophenyl)methyl]-3-{[4-(2-methylpropoxy)phenyl]methyl}-1-(piperidin-4-yl)urea|Smiles: CC(C)COC1=CC=C(CNC(=O)N(CC2=CC=C(F)C=C2)C2CCNCC2)C=C1|InChiKey: CJAUQHPXNICIJI-UHFFFAOYSA-N|InChi: InChI=1S/C24H32FN3O2/c1-18(2)17-30-23-9-5-19(6-10-23)15-27-24(29)28(22-11-13-26-14-12-22)16-20-3-7-21(25)8-4-20/h3-10,18,22,26H,11-17H2,1-2H3,(H,27,29)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.PMID:23907051 |Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|The mean plasma half-lives for Pimavanserin and its metabolite N-Desmethyl Pimavanserin (AC-279) are 57 hours and 200 hours, respectively.|Products are for research use only. Not for human use.|