Product Name :
FAK ligand-Linker Conjugate 1
Description:
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation.
CAS:
2307461-45-4
Molecular Weight:
583.58
Formula:
C25H28F3N5O6S
Chemical Name:
3-[2-(4-{[4-({[3-(N-methylmethanesulfonamido)phenyl]methyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenoxy)ethoxy]propanoic acid
Smiles :
CN(C1=CC(CNC2=NC(NC3C=CC(=CC=3)OCCOCCC(O)=O)=NC=C2C(F)(F)F)=CC=C1)S(C)(=O)=O
InChiKey:
OSVHAJNGZCDBGV-UHFFFAOYSA-N
InChi :
InChI=1S/C25H28F3N5O6S/c1-33(40(2,36)37)19-5-3-4-17(14-19)15-29-23-21(25(26,27)28)16-30-24(32-23)31-18-6-8-20(9-7-18)39-13-12-38-11-10-22(34)35/h3-9,14,16H,10-13,15H2,1-2H3,(H,34,35)(H2,29,30,31,32)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
FAK ligand-Linker Conjugate 1 incorporates a ligand for FAK, and a PROTAC linker, which recruit E3 ligases (such as VHL, CRBN, MDM2, and IAP). FAK ligand-Linker Conjugate 1 can be extensively used for PROTAC-mediated protein degradation.|Product information|CAS Number: 2307461-45-4|Molecular Weight: 583.58|Formula: C25H28F3N5O6S|Chemical Name: 3-[2-(4-{[4-({[3-(N-methylmethanesulfonamido)phenyl]methyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}phenoxy)ethoxy]propanoic acid|Smiles: CN(C1=CC(CNC2=NC(NC3C=CC(=CC=3)OCCOCCC(O)=O)=NC=C2C(F)(F)F)=CC=C1)S(C)(=O)=O|InChiKey: OSVHAJNGZCDBGV-UHFFFAOYSA-N|InChi: InChI=1S/C25H28F3N5O6S/c1-33(40(2,36)37)19-5-3-4-17(14-19)15-29-23-21(25(26,27)28)16-30-24(32-23)31-18-6-8-20(9-7-18)39-13-12-38-11-10-22(34)35/h3-9,14,16H,10-13,15H2,1-2H3,(H,34,35)(H2,29,30,31,32)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Batoclimab} web|{Batoclimab} Biological Activity|{Batoclimab} In Vivo|{Batoclimab} supplier|{Batoclimab} Epigenetics} |Shelf Life: ≥12 months if stored properly.{{Olacaftor} site|{Olacaftor} Membrane Transporter/Ion Channel|{Olacaftor} Protocol|{Olacaftor} In Vivo|{Olacaftor} custom synthesis|{Olacaftor} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:35126464 |Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|