Product Name :
MCX 28
Description:
MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.
CAS:
1414453-58-9
Molecular Weight:
549.64
Formula:
C25H19N5O4S3
Chemical Name:
25-methoxy-31-methyl-3, 22, 30-trithia-6, 8, 15, 23, 26-pentaazahexacyclo[22.3.1.1, .1, .1, .0, ]hentriaconta-1(27), 2(31), 4, 6, 8, 10, 12, 17(29), 18, 20, 24(28), 25-dodecaene-16
Smiles :
CC1C2=NC=NC3C4=CC=C(CNC(=O)C5=CC(=CC=C5)S(=O)(=O)NC5=CC(=CN=C5OC)C=1SC=32)S4
InChiKey:
LPJAKJUVEMSSSX-UHFFFAOYSA-N
InChi :
InChI=1S/C25H19N5O4S3/c1-13-20-23-21(29-12-28-20)19-7-6-16(35-19)11-26-24(31)14-4-3-5-17(8-14)37(32,33)30-18-9-15(22(13)36-23)10-27-25(18)34-2/h3-10,12,30H,11H2,1-2H3,(H,26,31)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
MCX 28, a triple PI3K/mTOR/PIM inhibitor, displays low nanomolar activity.|Product information|CAS Number: 1414453-58-9|Molecular Weight: 549.64|Formula: C25H19N5O4S3|Chemical Name: 25-methoxy-31-methyl-3, 22, 30-trithia-6, 8, 15, 23, 26-pentaazahexacyclo[22.3.1.1, .1, .1, .0, ]hentriaconta-1(27), 2(31), 4, 6, 8, 10, 12, 17(29), 18, 20, 24(28), 25-dodecaene-16|Smiles: CC1C2=NC=NC3C4=CC=C(CNC(=O)C5=CC(=CC=C5)S(=O)(=O)NC5=CC(=CN=C5OC)C=1SC=32)S4|InChiKey: LPJAKJUVEMSSSX-UHFFFAOYSA-N|InChi: InChI=1S/C25H19N5O4S3/c1-13-20-23-21(29-12-28-20)19-7-6-16(35-19)11-26-24(31)14-4-3-5-17(8-14)37(32,33)30-18-9-15(22(13)36-23)10-27-25(18)34-2/h3-10,12,30H,11H2,1-2H3,(H,26,31)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: To be determined|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{8-Hydroxy-2′-deoxyguanosine} site|{8-Hydroxy-2′-deoxyguanosine} Metabolic Enzyme/Protease|{8-Hydroxy-2′-deoxyguanosine} Protocol|{8-Hydroxy-2′-deoxyguanosine} In Vitro|{8-Hydroxy-2′-deoxyguanosine} supplier|{8-Hydroxy-2′-deoxyguanosine} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Sorafenib} medchemexpress|{Sorafenib} Autophagy|{Sorafenib} Purity & Documentation|{Sorafenib} Formula|{Sorafenib} supplier|{Sorafenib} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24463635 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Martínez-González S, et al. Macrocyclization as a Source of Desired Polypharmacology. Discovery of Triple PI3K/mTOR/PIM Inhibitors. ACS Med Chem Lett. 2021 Nov 2;12(11):1794-1801.Products are for research use only. Not for human use.|