Product Name :
Doxercalciferol-D3
Description:
Doxercalciferol-D3 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).
CAS:
2070009-32-2
Molecular Weight:
415.67
Formula:
C28H44O2
Chemical Name:
(1R, 3S, 5Z)-5-{2-[(1R, 3aS, 4E, 7aR)-1-[(2R, 3E, 5R)-5, 6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene](1-H)ethylidene}-4-(H)methylidenecyclohexane-1, 3-diol
Smiles :
[2H]C([2H])=C1[C@@H](O)C[C@H](O)C/C/1=C(\[2H])/C=C1\CCC[C@]2(C)[C@H](CC[C@H]2\1)[C@H](C)/C=C/[C@H](C)C(C)C
InChiKey:
HKXBNHCUPKIYDM-ZKEOFIQWSA-N
InChi :
InChI=1S/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1/i5D2,12D
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Doxercalciferol-D3 is the deuterated form of Doxercalciferol, which is a Vitamin D2 analog that acts as a vitamin D receptor activator (VDRA).|Product information|CAS Number: 2070009-32-2|Molecular Weight: 415.67|Formula: C28H44O2|Chemical Name: (1R, 3S, 5Z)-5-{2-[(1R, 3aS, 4E, 7aR)-1-[(2R, 3E, 5R)-5, 6-dimethylhept-3-en-2-yl]-7a-methyl-octahydro-1H-inden-4-ylidene](1-H)ethylidene}-4-(H)methylidenecyclohexane-1, 3-diol|Smiles: [2H]C([2H])=C1[C@@H](O)C[C@H](O)C/C/1=C(\[2H])/C=C1\CCC[C@]2(C)[C@H](CC[C@H]2\1)[C@H](C)/C=C/[C@H](C)C(C)C|InChiKey: HKXBNHCUPKIYDM-ZKEOFIQWSA-N|InChi: InChI=1S/C28H44O2/c1-18(2)19(3)9-10-20(4)25-13-14-26-22(8-7-15-28(25,26)6)11-12-23-16-24(29)17-27(30)21(23)5/h9-12,18-20,24-27,29-30H,5,7-8,13-17H2,1-4,6H3/b10-9+,22-11+,23-12-/t19-,20+,24+,25+,26-,27-,28+/m0/s1/i5D2,12D|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: Soluble in DMSO|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{D-Panthenol} web|{D-Panthenol} Endogenous Metabolite|{D-Panthenol} Technical Information|{D-Panthenol} In Vivo|{D-Panthenol} supplier|{D-Panthenol} Autophagy} |Shelf Life: ≥12 months if stored properly.{{Trastuzumab emtansine (solution)} MedChemExpress|{Trastuzumab emtansine (solution)} JAK/STAT Signaling|{Trastuzumab emtansine (solution)} Purity & Documentation|{Trastuzumab emtansine (solution)} Data Sheet|{Trastuzumab emtansine (solution)} supplier|{Trastuzumab emtansine (solution)} Autophagy} |Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:23907051 |Drug Formulation: To be determined|HS Tariff Code: 382200|References:|Brown AJ, Ritter CS, Knutson JC, Strugnell SA. The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells. Nephrol Dial Transplant. 2006 Mar;21(3):644-50.Noonan W, Koch K, Nakane M, Ma J, Dixon D, Bolin A, Reinhart G. Differential effects of vitamin D receptor activators on aortic calcification and pulse wave velocity in uraemic rats. Nephrol Dial Transplant. 2008 Dec;23(12):3824-30.Gran Sjdén. Effects of vitamin D. A comparison of 1 alpha OHD2 and 1 alpha OHD3 in rats.[J]. Acta Orthopaedica Scandinavica Supplementum, 1985, 217(1):1-84.Products are for research use only. Not for human use.|