Product Name :
Bullatine A
Description:
Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses. Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed.
CAS:
1354-84-3
Molecular Weight:
343.50
Formula:
C22H33NO2
Chemical Name:
(5R,11R,14S,15R,16R)-7-ethyl-5-methyl-12-methylidene-7-azahexacyclo[7.6.2.2¹⁰,¹³.0¹,⁸.0⁵,¹⁶.0¹⁰,¹⁵]nonadecane-11,14-diol
Smiles :
C[C@@]12CCCC34[C@@H]1CC(C3N(C2)CC)C12CCC([C@H](O)[C@@H]14)C(=C)[C@H]2O
InChiKey:
OVXLNQAYPUEDSI-LVIQKLEBSA-N
InChi :
InChI=1S/C22H33NO2/c1-4-23-11-20(3)7-5-8-22-15(20)10-14(18(22)23)21-9-6-13(12(2)19(21)25)16(24)17(21)22/h13-19,24-25H,2,4-11H2,1,3H3/t13?,14?,15-,16+,17+,18?,19-,20+,21?,22?/m1/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Imidazole} MedChemExpress|{Imidazole} Metabolic Enzyme/Protease|{Imidazole} Purity & Documentation|{Imidazole} Data Sheet|{Imidazole} manufacturer|{Imidazole} Autophagy}
Shelf Life:
≥12 months if stored properly.{{Sulindac} medchemexpress|{Sulindac} Immunology/Inflammation|{Sulindac} Protocol|{Sulindac} References|{Sulindac} supplier|{Sulindac} Autophagy}
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.PMID:24059181
Additional information:
Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects. Bullatine A is a potent P2X7 antagonist, inhibits ATP-induced cell death/apoptosis and P2X receptor-mediated inflammatory responses. Bullatine A attenuates pain hypersensitivity, regardless of the pain models employed.|Product information|CAS Number: 1354-84-3|Molecular Weight: 343.50|Formula: C22H33NO2|Chemical Name: (5R,11R,14S,15R,16R)-7-ethyl-5-methyl-12-methylidene-7-azahexacyclo[7.6.2.2¹⁰,¹³.0¹,⁸.0⁵,¹⁶.0¹⁰,¹⁵]nonadecane-11,14-diol|Smiles: C[C@@]12CCCC34[C@@H]1CC(C3N(C2)CC)C12CCC([C@H](O)[C@@H]14)C(=C)[C@H]2O|InChiKey: OVXLNQAYPUEDSI-LVIQKLEBSA-N|InChi: InChI=1S/C22H33NO2/c1-4-23-11-20(3)7-5-8-22-15(20)10-14(18(22)23)21-9-6-13(12(2)19(21)25)16(24)17(21)22/h13-19,24-25H,2,4-11H2,1,3H3/t13?,14?,15-,16+,17+,18?,19-,20+,21?,22?/m1/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|