Year: 2024

Product Name : FenretinideDescription:Fenretinide is an orally-active synthetic phenylretinamide analogue of retinol (vitamin A) with potential antineoplastic and chemopreventive activities. Fenretinide binds to and activates retinoic acid receptors (RARs), thereby…

Product Name : PD158780Description:PD 158780 is a potent in vitro inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) (IC50 0.08 nM), and other members of…

Product Name : SGI-1027 --- DNMT InhibitorDescription:SGI-1027 is a potent DNMT inhibitor, which reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation. Treatment of different…

Product Name : A769662 --- AMPK ActivatorDescription:A769662 is a potent and selective small-molecule activator of AMP-activated protein kinase (AMPK). It induces allosteric activation of AMPK and inhibition of dephosphorylation of…

Product Name : IGF-I (24-41)Description:IGF-I (24-41) is amino acids 24 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses…

Product Name : L-Cysteic acid monohydrateDescription:L-Cysteic acid monohydrate is an endogenous metabolite.CAS: 23537-25-9Molecular Weight:187.17Formula: C3H9NO6SChemical Name: (2R)-2-amino-3-sulfopropanoic acid hydrateSmiles : O.N[C@@H](CS(O)(=O)=O)C(O)=OInChiKey: PCPIXZZGBZWHJO-DKWTVANSSA-NInChi : InChI=1S/C3H7NO5S.H2O/c4-2(3(5)6)1-10(7,8)9;/h2H,1,4H2,(H,5,6)(H,7,8,9);1H2/t2-;/m0./s1Purity: ≥98% (or refer to the Certificate…

Product Name : N-Desmethyl imatinib D8Description:N-Desmethyl imatinib D8 (Norimatinib D8) is a deuterium labeled Imatinib metabolite N-Desmethyl Imatinib.CAS: 1185103-28-9Molecular Weight:487.63Formula: C28H29N7OChemical Name: N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-{[(2,2,3,3,5,5,6,6-²H₈)piperazin-1-yl]methyl}benzamideSmiles : [2H]C1([2H])NC([2H])([2H])C([2H])([2H])N(CC2C=CC(=CC=2)C(=O)NC2=CC(NC3=NC(=CC=N3)C3=CN=CC=C3)=C(C)C=C2)C1([2H])[2H]InChiKey: BQQYXPHRXIZMDM-DBVREXLBSA-NInChi : InChI=1S/C28H29N7O/c1-20-4-9-24(17-26(20)34-28-31-12-10-25(33-28)23-3-2-11-30-18-23)32-27(36)22-7-5-21(6-8-22)19-35-15-13-29-14-16-35/h2-12,17-18,29H,13-16,19H2,1H3,(H,32,36)(H,31,33,34)/i13D2,14D2,15D2,16D2Purity: ≥98% (or…

Product Name : ZINC13466751Description:ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM.CAS: 117953-17-0Molecular Weight:363.41Formula: C20H21N5O2Chemical Name: 5-methyl-4-{2-[4-(morpholin-4-yl)phenyl]diazen-1-yl}-2-phenyl-2,3-dihydro-1H-pyrazol-3-oneSmiles : CC1NN(C(=O)C=1N=NC1C=CC(=CC=1)N1CCOCC1)C1C=CC=CC=1InChiKey: BPLMVWHZMFTKIE-QURGRASLSA-NInChi : InChI=1S/C20H21N5O2/c1-15-19(20(26)25(23-15)18-5-3-2-4-6-18)22-21-16-7-9-17(10-8-16)24-11-13-27-14-12-24/h2-10,23H,11-14H2,1H3/b22-21+Purity: ≥98% (or…

Product Name : COH-SR4Description:COH-SR4 is an AMPK activator. COH-SR4 shows potent anti-proliferative activities against leukemia, melanoma, breast and lung cancers. COH-SR4 inhibits adipocyte differentiation via AMPK activation. COH-SR4 can be…

Product Name : TectorusideDescription:Tectoruside is a phenol acid glycoside of the rhizome of Iris dichotoma Pall. Iris dichotoma Pall, a traditional Chinese herbal medicine, has been used in several disorders…