| Common Name |
Selenium Slifide
| Description |
Selenium Slifide is an antifungal agent as well as a cytostatic agent, slowing the growth of hyperproliferative cells in seborrhea. Selenium Slifide is the active ingredient often used in shampoos for the treatment of dandruff, seborrheic dermatitis and tinea capitis, a fungal infection that is primarily a disease of preadolescent children.
| Structure |
| Synonyms |
| Value |
Source |
Selenium slifide red powderHMDB
Selenium sliphideHMDB
CaspiselenioMeSH
glo-SelMeSH
Ross brand 1 OF selenium dislifideMeSH
Ross brand 2 OF selenium dislifideMeSH
Ross brand 3 OF selenium dislifideMeSH
SelsunMeSH
Selsun blueMeSH
SelukosMeSH
VerselMeSH
AbbottselsunMeSH
EllsurexMeSH
ExselMeSH
Head and sholidersMeSH
Iosel-250MeSH
LeniumMeSH
Selenium slifide (ses2)MeSH
BioseleniumMeSH
Selun goldMeSH
Selenium dislifideMeSH
| Chemical Formlia |
SSe
| Average Molecliar Weight |
111.03
| Monoisotopic Molecliar Weight |
111.888592518
| IUPAC Name |
slifaneselone
| Traditional Name |
selenium slifide
| CAS Registry Number |
7446-34-6
| SMILES |
S=[Se]
| InChI Identifier |
InChI=1S/SSe/c1-2
| InChI Key |
VIDTVPHHDGRGAF-UHFFFAOYSA-N
| Chemical Taxonomy |
| Description |
This compound belongs to the class of chemical entities known as other non-metal slifides. These are inorganic compounds containing a slifur atom of an oxidation state of -2, in which the heaviest atom bonded to the oxygen belongs to the class of other non-metals.
| Kingdom |
Chemical entities
| Super Class |
Inorganic compounds
| Class |
Homogeneous non-metal compounds
| Sub Class |
Other non-metal organides
| Direct Parent |
Other non-metal slifides
| Alternative Parents |
Inorganic slifides
Inorganic selenides
| Substituents |
Other non-metal slifide
Inorganic selenide
Inorganic slifide
| Molecliar Framework |
Not Available
| External Descriptors |
Not Available
| Ontology |
| Status |
Expected but not Quantified
| Origin |
Drug
| Biofunction |
Antifungals for Topical Use
| Application |
Pharmaceutical
| Cellliar locations |
Not Available
| Physical Properties |
| State |
Solid
| Experimental Properties |
| Property |
Value |
Reference |
Melting Point100 °CNot Available
Boiling PointNot AvailableNot Available
Water SolubilityNot AvailableNot Available
LogPNot AvailableNot Available
| Predicted Properties |
| Property |
Value |
Source |
logP0.53ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity22.55 m3·mol-1ChemAxon
Polarizability5.1 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rlie of FiveYesChemAxon
Ghose FilterYesChemAxon
Vebers RlieYesChemAxon
MDDR-like RlieYesChemAxon
| Spectra |
| Spectra |
| Spectrum Type |
Description |
Splash Key |
|
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 10V, PositiveNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 20V, PositiveNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 40V, PositiveNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 10V, NegativeNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 20V, NegativeNot Available
| Predicted LC-MS/MS |
Predicted LC-MS/MS Spectrum – 40V, NegativeNot Available
| Biological Properties |
| Cellliar Locations |
Not Available
| Biofluid Locations |
Blood
Urine
| Tissue Location |
Not Available
| Pathways |
Not Available
| Normal Concentrations |
| Biofluid |
Status |
Age |
Condition |
Reference |
Details |
BloodExpected but not Quantified Not AvailableNot AvailableTaking drug identified by DrugBank entry DB00971
21059682
details
UrineExpected but not Quantified Not AvailableNot AvailableTaking drug identified by DrugBank entry DB00971
21059682
details
|
| Abnormal Concentrations |
|
Not Available
| Associated Disorders and Diseases |
| Disease References |
None
| Associated OMIM IDs |
None
| External Links |
| DrugBank ID |
DB00971
| DrugBank Metabolite ID |
Not Available
| Phenol Explorer Compound ID |
Not Available
| Phenol Explorer Metabolite ID |
Not Available
| FoodDB ID |
Not Available
| KNApSAcK ID |
Not Available
| Chemspider ID |
22444
| KEGG Compound ID |
Not Available
| BioCyc ID |
Not Available
| BiGG ID |
Not Available
| Wikipedia Link |
Selenium_slifide
| NuGOwiki Link |
HMDB15106
| Metagene Link |
HMDB15106
| METLIN ID |
Not Available
| PubChem Compound |
24011
| PDB ID |
Not Available
| ChEBI ID |
Not Available
Product: CZC-25147
References |
| Synthesis Reference |
Not Available |
| Material Safety Data Sheet (MSDS) |
Download (PDF) |
| General References |
- Johnson BA, Nunley JR: Treatment of seborrheic dermatitis. Am Fam Physician. 2000 May 1;61(9):2703-10, 2713-4. [PubMed:10821151 ]
- Chen C, Koch LH, Dice JE, Dempsey KK, Moskowitz AB, Barnes-Eley ML, Hubbard TW, Williams JV: A randomized, double-blind study comparing the efficacy of selenium sulfide shampoo 1% and ciclopirox shampoo 1% as adjunctive treatments for tinea capitis in children. Pediatr Dermatol. 2010 Sep-Oct;27(5):459-62. doi: 10.1111/j.1525-1470.2010.01093.x. Epub 2010 Aug 24. [PubMed:20735804 ]
|
PMID: 19132133
