Kaempferol 3-glucuronide
Kaempferol 3-glucuronide is found in chicory. Kaempferol 3-glucuronide is isolated from the leaves of Euphorbia lathyris, Euphorbia cyparissias, Anemone alpina and Phaseolus vligaris (kidney bean) and many other plants [CCD]Kaempferol 3-glucuronide belongs to the family of Flavonoid O-Glycosides. These are compounds containing a carbohydrate moiety which is o-glycosidically linked to one of the flavonoid backbones (2-phenylchromen-4-one, 3-phenylchromen-4-one or 4-phenylcoumarin).
Structure for HMDB29500 (Kaempferol 3-glucuronide)
C21H18O12
462.3604
462.07982604
6-{[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
6-{[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
22688-78-4
FNTJVYCFNVUBOL-UHFFFAOYSA-N
This compound belongs to the class of chemical entities known as flavonoid-3-o-glucuronides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to glucuronic acid at the C3-position.
Chemical entities
Organic compounds
Phenylpropanoids and polyketides
Flavonoids
Flavonoid-3-O-glucuronides
Aromatic heteropolycyclic compounds
Not Available
Detected but not Quantified
Not Available
Predicted LC-MS/MS Spectrum – 10V, Positivesplash10-000j-0170900000-1e4e727a77229b6993ebView in MoNA
Predicted LC-MS/MS Spectrum – 20V, Positivesplash10-000i-0090100000-404ced678a3392b5aa5cView in MoNA
Predicted LC-MS/MS Spectrum – 40V, Positivesplash10-00kr-2590000000-d78ceaa8baa9bf67cd33View in MoNA
Predicted LC-MS/MS Spectrum – 10V, Positivesplash10-000j-0170900000-1e4e727a77229b6993ebView in MoNA
Predicted LC-MS/MS Spectrum – 20V, Positivesplash10-000i-0090100000-404ced678a3392b5aa5cView in MoNA
Predicted LC-MS/MS Spectrum – 40V, Positivesplash10-00kr-2590000000-d78ceaa8baa9bf67cd33View in MoNA
Predicted LC-MS/MS Spectrum – 10V, Negativesplash10-03dr-1141900000-2de4c77a59276fcc79f4View in MoNA
Predicted LC-MS/MS Spectrum – 20V, Negativesplash10-000i-2191200000-821a7aa34257929af469View in MoNA
Predicted LC-MS/MS Spectrum – 40V, Negativesplash10-000i-3490000000-03573ca62c35318e4268View in MoNA
Predicted LC-MS/MS Spectrum – 10V, Negativesplash10-03dr-1141900000-2de4c77a59276fcc79f4View in MoNA
Predicted LC-MS/MS Spectrum – 20V, Negativesplash10-000i-2191200000-821a7aa34257929af469View in MoNA
Predicted LC-MS/MS Spectrum – 40V, Negativesplash10-000i-3490000000-03573ca62c35318e4268View in MoNA
Not Available
Normal
Not Available
None
None
Not Available
Not Available
305
Not Available
FDB000634
C00005141
11500908
Not Available
Not Available
Not Available
Not Available
HMDB29500
HMDB29500
Not Available
14185731
Not Available
Not Available
- (). Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.. .
Enzymes
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
- Gene Name:
- UGT2B4
- Uniprot ID:
- P06133
- Molecular weight:
- 60512.035
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate.
- Gene Name:
- UGT1A4
- Uniprot ID:
- P22310
- Molecular weight:
- 60024.535
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites. Is also active with androsterone, hyodeoxycholic acid and tetrachlorocatechol (in vitro).
- Gene Name:
- UGT2B7
- Uniprot ID:
- P16662
- Molecular weight:
- 60720.15
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.
- Gene Name:
- UGT1A1
- Uniprot ID:
- P22309
- Molecular weight:
- 59590.91
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
- Gene Name:
- UGT1A9
- Uniprot ID:
- O60656
- Molecular weight:
- 59940.495
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
- Gene Name:
- UGT1A6
- Uniprot ID:
- P19224
- Molecular weight:
- 60750.215
Kaempferol 3-glucuronide
Kaempferol 3-glucuronide
Kaempferol 3-glucuronide is found in chicory. Kaempferol 3-glucuronide is isolated from the leaves of Euphorbia lathyris, Euphorbia cyparissias, Anemone alpina and Phaseolus vligaris (kidney bean) and many other plants [CCD]Kaempferol 3-glucuronide belongs to the family of Flavonoid O-Glycosides. These are compounds containing a carbohydrate moiety which is o-glycosidically linked to one of the flavonoid backbones (2-phenylchromen-4-one, 3-phenylchromen-4-one or 4-phenylcoumarin).
Structure for HMDB29500 (Kaempferol 3-glucuronide)
C21H18O12
462.3604
462.07982604
6-{[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
6-{[5,7-dihydroxy-2-(4-hydroxyphenyl)-4-oxochromen-3-yl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid
22688-78-4
FNTJVYCFNVUBOL-UHFFFAOYSA-N
This compound belongs to the class of chemical entities known as flavonoid-3-o-glucuronides. These are phenolic compounds containing a flavonoid moiety which is O-glycosidically linked to glucuronic acid at the C3-position.
Chemical entities
Organic compounds
Phenylpropanoids and polyketides
Flavonoids
Flavonoid-3-O-glucuronides
Aromatic heteropolycyclic compounds
Not Available
Detected but not Quantified
Not Available
Predicted LC-MS/MS Spectrum – 10V, Positivesplash10-000j-0170900000-1e4e727a77229b6993ebView in MoNA
Predicted LC-MS/MS Spectrum – 20V, Positivesplash10-000i-0090100000-404ced678a3392b5aa5cView in MoNA
Predicted LC-MS/MS Spectrum – 40V, Positivesplash10-00kr-2590000000-d78ceaa8baa9bf67cd33View in MoNA
Predicted LC-MS/MS Spectrum – 10V, Positivesplash10-000j-0170900000-1e4e727a77229b6993ebView in MoNA
Predicted LC-MS/MS Spectrum – 20V, Positivesplash10-000i-0090100000-404ced678a3392b5aa5cView in MoNA
Predicted LC-MS/MS Spectrum – 40V, Positivesplash10-00kr-2590000000-d78ceaa8baa9bf67cd33View in MoNA
Predicted LC-MS/MS Spectrum – 10V, Negativesplash10-03dr-1141900000-2de4c77a59276fcc79f4View in MoNA
Predicted LC-MS/MS Spectrum – 20V, Negativesplash10-000i-2191200000-821a7aa34257929af469View in MoNA
Predicted LC-MS/MS Spectrum – 40V, Negativesplash10-000i-3490000000-03573ca62c35318e4268View in MoNA
Predicted LC-MS/MS Spectrum – 10V, Negativesplash10-03dr-1141900000-2de4c77a59276fcc79f4View in MoNA
Predicted LC-MS/MS Spectrum – 20V, Negativesplash10-000i-2191200000-821a7aa34257929af469View in MoNA
Predicted LC-MS/MS Spectrum – 40V, Negativesplash10-000i-3490000000-03573ca62c35318e4268View in MoNA
Not Available
Normal
Not Available
None
None
Not Available
Not Available
305
Not Available
FDB000634
C00005141
11500908
Not Available
Not Available
Not Available
Not Available
HMDB29500
HMDB29500
Not Available
14185731
Not Available
Not Available
- (). Yannai, Shmuel. (2004) Dictionary of food compounds with CD-ROM: Additives, flavors, and ingredients. Boca Raton: Chapman & Hall/CRC.. .
Enzymes
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4-nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol). It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.
- Gene Name:
- UGT2B4
- Uniprot ID:
- P06133
- Molecular weight:
- 60512.035
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate.
- Gene Name:
- UGT1A4
- Uniprot ID:
- P22310
- Molecular weight:
- 60024.535
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.Its unique specificity for 3,4-catechol estrogens and estriol suggests it may play an important role in regulating the level and activity of these potent and active estrogen metabolites. Is also active with androsterone, hyodeoxycholic acid and tetrachlorocatechol (in vitro).
- Gene Name:
- UGT2B7
- Uniprot ID:
- P16662
- Molecular weight:
- 60720.15
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform glucuronidates bilirubin IX-alpha to form both the IX-alpha-C8 and IX-alpha-C12 monoconjugates and diconjugate. Is also able to catalyze the glucuronidation of 17beta-estradiol, 17alpha-ethinylestradiol, 1-hydroxypyrene, 4-methylumbelliferone, 1-naphthol, paranitrophenol, scopoletin, and umbelliferone.
- Gene Name:
- UGT1A1
- Uniprot ID:
- P22309
- Molecular weight:
- 59590.91
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
- Gene Name:
- UGT1A9
- Uniprot ID:
- O60656
- Molecular weight:
- 59940.495
- General function:
- Involved in transferase activity, transferring hexosyl groups
- Specific function:
- UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.
- Gene Name:
- UGT1A6
- Uniprot ID:
- P19224
- Molecular weight:
- 60750.215