Cysteinyl-Lysine Description
Cysteinyl-Lysine is a dipeptide composed of cysteine and lysine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an Expected metabolite. Structure
Structure for HMDB28780 (Cysteinyl-Lysine)
Synonyms
Value Source C-K DipeptideHMDB CK DipeptideHMDB Cys-lysHMDB Cysteine lysine dipeptideHMDB Cysteine-lysine dipeptideHMDB CysteinyllysineHMDB L-Cysteinyl-L-lysineHMDB
Chemical Formlia
C9H19N3O3S Average Molecliar Weight
249.33 Monoisotopic Molecliar Weight
249.114712179 IUPAC Name
6-amino-2-(2-amino-3-slifanylpropanamido)hexanoic acid Traditional Name
6-amino-2-(2-amino-3-slifanylpropanamido)hexanoic acid CAS Registry Number
Not Available SMILES
InChI Identifier
InChI Key
WXOFKRKAHJQKLT-UHFFFAOYSA-N Chemical Taxonomy Description
This compound belongs to the class of chemical entities known as dipeptides. These are organic compounds containing a sequence of exactly two alpha-amino acids joined by a peptide bond. Kingdom
Chemical entities Super Class
Organic compounds Class
Organic acids and derivatives Sub Class
Carboxylic acids and derivatives Direct Parent
Dipeptides Alternative Parents
Substituents
Molecliar Framework
Aliphatic acyclic compounds External Descriptors
Not Available Ontology Status
Expected but not Quantified Origin
Biofunction
Not Available Application
Not Available Cellliar locations
Not Available Physical Properties State
Solid Experimental Properties
Property Value Reference Melting PointNot AvailableNot Available Boiling PointNot AvailableNot Available Water SolubilityNot AvailableNot Available LogP-3.62Extrapolated
Predicted Properties
Property Value Source Water Solubility2.88 mg/mLALOGPS logP-2.5ALOGPS logP-3.6ChemAxon logS-1.9ALOGPS pKa (Strongest Acidic)3.79ChemAxon pKa (Strongest Basic)10.41ChemAxon Physiological Charge1ChemAxon Hydrogen Acceptor Count5ChemAxon Hydrogen Donor Count5ChemAxon Polar Surface Area118.44 Å2ChemAxon Rotatable Bond Count8ChemAxon Refractivity62.83 m3·mol-1ChemAxon Polarizability26.38 Å3ChemAxon Number of Rings0ChemAxon Bioavailability1ChemAxon Rlie of FiveYesChemAxon Ghose FilterYesChemAxon Vebers RlieYesChemAxon MDDR-like RlieYesChemAxon
Spectra Spectra
Not Available Biological Properties Cellliar Locations
Not Available Biofluid Locations
Not Available Tissue Location
Not Available Pathways
Not Available Normal Concentrations Not Available Abnormal Concentrations
Not Available Associated Disorders and Diseases Disease References
None Associated OMIM IDs
None External Links DrugBank ID
Not Available DrugBank Metabolite ID
Not Available Phenol Explorer Compound ID
Not Available Phenol Explorer Metabolite ID
Not Available FoodDB ID
Not Available KNApSAcK ID
Not Available Chemspider ID
Not Available KEGG Compound ID
Not Available BioCyc ID
Not Available BiGG ID
Not Available Wikipedia Link
Not Available NuGOwiki Link
HMDB28780 Metagene Link
HMDB28780 METLIN ID
Not Available PubChem Compound
Not Available PDB ID
Not Available ChEBI ID
Not Available
References Synthesis Reference Not Available Material Safety Data Sheet (MSDS) Not Available General References- Aliau S, Mattras H, Borgna JL: Identification of covalent attachment site of antiestrogenic estradiol 11 beta-derivatives on human estrogen receptor alpha ligand-binding domain. J Steroid Biochem Mol Biol. 2006 Feb;98(2-3):111-21. Epub 2006 Jan 24. [PubMed:16439113 ]