Binding affinity of the indicated STAT1-GFP fusion proteins to a few unique duplex oligonucleotides that contains two strong Fuel aspects in tandem arrangement (2xGAS) or mutations thereof, with a one Gas ingredient (Fuel-nonGAS) or no Gasoline component (2xnonGAS)
Substitution of glutamine residues in place 559 and 563 final results in STAT1 mutants with a extended IFNc-induced nuclear accumulation. (A, B) HeLa cells expressing GFP fusion proteins with both…