The activation of PPAR by 5 M resveratrol, T4HS, or 4-PAP was enhanced by rolipram, a PDE4 inhibitor, or forskolin, an adenylate cyclase activator, the two of which enhance intracellular cAMP levels, even though rolipram or forskolin alone could not activate PPAR

The activation of PPAR by five M resveratrol, T4HS, or four-PAP was improved by rolipram, a PDE4 inhibitor, or forskolin, an adenylate cyclase activator, the two of which boost intracellular…