Besides its role as a gasoline, lactate was proposed to inhibit PHD2 in normoxic TCs, an activity that would involve lactate oxidation to pyruvate and a levels of competition between pyruvate and 2-oxoglutarate
The higher panels exhibit agent experiments and the graphs HIF-1a protein expression normalized to b-actin amounts. ns, p..05, p,.01, p,.005. (C) The amount of VEGF-A transcript was established employing RT-qPCR…