For this reason, mice underwent SNI surgical treatment and had been i.p. handled with a mixture of lower dose Vit C+E or with saline 30 min right after SNI surgical procedure, followed by oncedaily i.p. administration
Similar experimental location as described in Figure three, but with intrathecal drug administration at the indicated doses. The Vit C+E mixture efficiently inhibited SNIinducedRutoside mechanical allodynia soon after i.t. administration.…