FCMs look polarised towards M1 when extracted from human plaques [sixty eight] and rabbit granulomas [21,22], to M2 when extracted from the peritoneum of LDL receptor null mice [23] or neither M1 nor M2 when extracted from mouse subcutaneous granulomas in this study
Even so, substantially previous literature establishes that TGF can stimulate collagen synthesis in the plaques [29,35], as properly as through the advancement of restenosis [55]. Proteolytic activation of latent TGF,…