APE1 has been found not only to be required for animal viability, as deletion of both alleles of the APE1 gene in mice leads to embryonic lethality, but also for…
AbstractResistance to insecticides has become a critical issue in pest management and it is particularly chronic in the control of human disease vectors. The gravity of this situation is being…
Citation: Coffey K, Blackburn TJ, Cook S, Golding BT, Griffin RJ, et al. (2012) Characterisation of a Tip60 Specific Inhibitor, NU9056, in Prostate Cancer. PLoS ONE 7(10): e45539. doi:10.1371/journal.pone.0045539 Editor:…
DiscussionThe SKs are becoming increasingly recognized as potential new targets for anticancer drugs; however, the literature provides differing views on the relative importance of SK1 and SK2 in cancer biology.…